Leica M 205 m/c/a Stereo Microscope
Advanced Fluorescence Stereo Microscope
The Leica M205 FCA is an advanced semi-automated fluorescence stereo microscope designed to capture both fast and highly detailed images of your research samples. Perfect for those working with faint fluorescence signals such as GFP and mCherry, this system enables efficient and precise detection, ensuring you capture even the faintest signals early on.
Key Features Of Leica M205 FCA
- FusionOptics Technology:
Leica’s FusionOptics combines high resolution and a large depth of field (DOF) for unparalleled image clarity. It delivers exceptional details in 3D, allowing you to visualize intricate structures with incredible precision. - Bright Fluorescence Signals:
With separate, synchronized beam paths for fluorescence excitation and two observation channels, the M205 FCA offers fully illuminated, clear images, ensuring sharp, bright fluorescence signals in every zoom position. - TripleBeam Technology:
Leica’s innovative TripleBeam technology eliminates background noise, providing a clear, strong fluorescence signal against a black, noise-free background. This allows for superior image quality, even with the faintest signals. - Motorized and Manual Control:
The Leica M205 FCA offers the flexibility of both semi-automation and manual control. It combines the convenience of fast manual zoom for screening with the precision of motorized zoom for capturing high-end, detailed fluorescence images. - Image Coding and Real-time Settings:
The M205 FCA integrates image coding, storing all parameters with your image for reproducible results. This includes automatic updates of magnification, iris diaphragm positions, and scale bars, making it easy to document and revisit your experiments. - High Magnification and Resolution:
With a resolution of 1279 lp/mm and the Leica 2x PlanApo objective, the M205 FCA offers detailed images, even at high magnifications. The high numerical aperture ensures clarity, revealing even the finest details at sub-um levels. - Advanced Software Compatibility (LAS X):
The M205 FCA integrates seamlessly with Leica’s LAS X software platform. This allows you to run and manage complex fluorescence experiments, from setting up to analyzing results, providing a streamlined workflow for researchers.
Leica M205 FCA Specifications
| Feature | Details |
|---|---|
| Optical System | Fully apochromatic optics with FusionOptics technology |
| Zoom Ratio | 20.5:1 manual zoom |
| Maximum Resolution | Up to 1279 lp/mm or 0.78 µm (ISO18221 standard) |
| Objective | 2.0x PlanApo objective with a maximum numerical aperture of 0.35 |
| Magnification Range | Standard magnification of 8x – 160x |
| Depth of Field | Enhanced depth of field due to FusionOptics |
| Excitation Light | Energy-rich excitation light for bright fluorescence signals |
| TripleBeam Technology | Separates fluorescence excitation light from observation channels to reduce background noise |
| Stage | Leica LMT 260 scanning stage for precise positioning |
| Filter Changer | Four position coded filter changer for quick adjustments |
| Automated Features | Semi-automated with manual zoom; optional fully motorized version available (M205 FA) |
| Ergonomics | Footswitch option for hands-free operation |
Applications Of Leica M205 FCA
- Transgenic Research: Ideal for detecting transgenic expression like GFP and mCherry in early developmental stages.
- Neuroscience Studies: Perfect for imaging complex neural structures and tissues in model organisms like zebrafish and C. elegans.
- Cell Culture Imaging: Suitable for observing live or fixed cell cultures, including stem cells and neuronal cells.
- Developmental Biology: Great for detailed imaging of early-stage embryos and larvae, especially in marine and aquatic species.
- Immunohistochemistry: Supports fluorescence imaging for tissue samples stained with various antibodies.
- Live Cell Imaging: Enables observation of live cell dynamics with high resolution and depth of field.
- Fluorescent Protein Studies: Ideal for imaging fluorescent proteins in research focused on gene expression and protein localization.
- Zebrafish Models: Excellent for in vivo imaging of zebrafish larvae expressing fluorescent proteins for studying disease models and developmental processes.
Why Choose Leica M205 FCA?
- Speed and Efficiency: Capture fast, reliable results without compromising on quality.
- Unmatched Image Quality: High resolution, depth of field, and noise-free fluorescence for the clearest images.
- Flexibility: Manual and motorized options for versatile use across different workflows.
- Seamless Workflow: Integrated image coding and LAS X software for easy documentation and analysis.
Leica M205 FCA empowers your research by simplifying fluorescence imaging while maintaining top-tier performance, speed, and accuracy. Whether you need quick screening or high-quality detailed imaging, this microscope delivers the perfect solution.
